TOP1 - PPP2R2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
PPP2R2A	ENSG00000221914	No diseases in record	No drugs in record	protein serine/threonine phosphatase activity protein binding protein phosphatase regulator activity protein complex binding tau protein binding protein phosphatase 2A binding	CDC55 (S. cerevisiae) sur-6 (C. elegans) tws (D. melanogaster)