IST1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IST1	ENSG00000182149	No diseases in record	No drugs in record	protein binding protein domain specific binding protein complex binding MIT domain binding cadherin binding involved in cell-cell adhesion molecular_function	IST1 (S. cerevisiae) istr-1 (C. elegans) CG10103 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)