TYMS - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TYMS	ENSG00000176890	No diseases in record	CAPECITABINE FLOXURIDINE FLUOROURACIL GEMCITABINE PEMETREXED	nucleotide binding mRNA binding thymidylate synthase activity folic acid binding drug binding protein homodimerization activity cofactor binding	CDC21 (S. cerevisiae) Ts (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)