FUS - PTEN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FUS	ENSG00000089280	liposarcoma AML Ewing sarcoma angiomatoid fibrous histiocytoma fibromyxoid sarcoma	No drugs in record	nucleotide binding DNA binding transcription coactivator activity RNA binding protein binding zinc ion binding estrogen receptor binding myosin V binding ionotropic glutamate receptor binding identical protein binding retinoid X receptor binding thyroid hormone receptor binding mRNA binding	No GO terms in record
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)