PTEN - ERN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)
ERN1	ENSG00000178607	No diseases in record	No drugs in record	magnesium ion binding endoribonuclease activity protein serine/threonine kinase activity platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding Hsp70 protein binding identical protein binding protein homodimerization activity ADP binding Hsp90 protein binding	IRE1 (S. cerevisiae) ire-1 (C. elegans) Ire1 (D. melanogaster)