TAF4 - MAP2K1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF4	ENSG00000130699	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding transcription factor binding protein heterodimerization activity transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription factor activity, sequence-specific DNA binding chromatin binding RNA polymerase II activating transcription factor binding TFIIA-class transcription factor binding transcription factor activity, core RNA polymerase II binding	taf-4 (C. elegans) Taf4 (D. melanogaster)
MAP2K1	ENSG00000169032	NSCLC melanoma colorectal	TRAMETINIB	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine phosphatase activity protein binding ATP binding protein C-terminus binding protein kinase binding protein serine/threonine kinase activator activity protein N-terminus binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)