UPF1 - MAP2K1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UPF1	ENSG00000005007	No diseases in record	No drugs in record	chromatin binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding zinc ion binding telomeric DNA binding DNA binding	NAM7 (S. cerevisiae) smg-2 (C. elegans) Upf1 (D. melanogaster)
MAP2K1	ENSG00000169032	NSCLC melanoma colorectal	TRAMETINIB	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine phosphatase activity protein binding ATP binding protein C-terminus binding protein kinase binding protein serine/threonine kinase activator activity protein N-terminus binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)