MCM4 - MAP2K1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM4	ENSG00000104738	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity DNA replication origin binding DNA binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity nucleotide binding single-stranded DNA-dependent ATPase activity hydrolase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity chromatin binding	MCM4 (S. cerevisiae) dpa (D. melanogaster)
MAP2K1	ENSG00000169032	NSCLC melanoma colorectal	TRAMETINIB	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine phosphatase activity protein binding ATP binding protein C-terminus binding protein kinase binding protein serine/threonine kinase activator activity protein N-terminus binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)