KMT2D - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KMT2D	ENSG00000167548	medulloblastoma renal	No drugs in record	DNA binding protein binding zinc ion binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K4 specific) transcription regulatory region DNA binding	SET1 (S. cerevisiae) set-16 (C. elegans) trr (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)