CASP8 - TP63

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
TP63	ENSG00000073282	HNSCC DLBCL NSCLC	No drugs in record	transcription factor activity, transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding p53 binding DNA binding chromatin binding damaged DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding identical protein binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding WW domain binding	No GO terms in record