CASP8 - ERCC5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
ERCC5	ENSG00000134899	skin basal cell skin squamous cell melanoma	No drugs in record	bubble DNA binding double-stranded DNA binding single-stranded DNA binding endodeoxyribonuclease activity protein binding protein homodimerization activity metal ion binding protein N-terminus binding	RAD2 (S. cerevisiae) xpg-1 (C. elegans)