CASP8 - CDK7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
CDK7	ENSG00000134058	No diseases in record	No drugs in record	transcription coactivator activity protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity kinase activity androgen receptor binding transcription factor activity, core RNA polymerase binding	KIN28 (S. cerevisiae) cdk-7 (C. elegans) Cdk7 (D. melanogaster)