MRE11 - CASP8

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MRE11 ENSG00000020922

No diseases in record

No drugs in record

hydrolase activity
exonuclease activity
endonuclease activity
protein complex scaffold activity
manganese ion binding
nuclease activity
3'-5' exonuclease activity
G-quadruplex DNA binding
single-stranded telomeric DNA binding
double-stranded telomeric DNA binding
telomeric DNA binding
endodeoxyribonuclease activity
adenylate kinase activity
protein binding
DNA end binding
single-stranded DNA endodeoxyribonuclease activity
Y-form DNA binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
MRE11 (S. cerevisiae)
mre-11 (C. elegans)
CASP8 ENSG00000064012 hepatocellular
oral squamous cell
breast

No drugs in record

cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)