CASP8 - ERN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
ERN1	ENSG00000178607	No diseases in record	No drugs in record	magnesium ion binding endoribonuclease activity protein serine/threonine kinase activity platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding Hsp70 protein binding identical protein binding protein homodimerization activity ADP binding Hsp90 protein binding	IRE1 (S. cerevisiae) ire-1 (C. elegans) Ire1 (D. melanogaster)