ATM - TOP1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)
TOP1 ENSG00000198900 AML*
IRINOTECAN
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
protein binding
isomerase activity
DNA topoisomerase activity
TOP1 (S. cerevisiae)
top-1 (C. elegans)
Top1 (D. melanogaster)