ATM - PTEN

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)
PTEN ENSG00000283094 glioma
prostate
endometrial
harmartoma

No drugs in record

magnesium ion binding
phosphatidylinositol-3-phosphatase activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
platelet-derived growth factor receptor binding
protein binding
protein tyrosine/serine/threonine phosphatase activity
lipid binding
anaphase-promoting complex binding
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
enzyme binding
protein kinase binding
PDZ domain binding
identical protein binding
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
actin binding
daf-18 (C. elegans)
Pten (D. melanogaster)