SKP1 - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SKP1	ENSG00000113558	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding beta-catenin binding cullin family protein binding ubiquitin protein ligase activity DNA replication origin binding DNA binding	SKP1 (S. cerevisiae) skr-2 (C. elegans) skr-1 (C. elegans) skr-17 (C. elegans) skr-9 (C. elegans) skr-8 (C. elegans) skr-7 (C. elegans) skr-18 (C. elegans) skr-10 (C. elegans) skr-13 (C. elegans) skr-12 (C. elegans) SkpA (D. melanogaster) SkpE (D. melanogaster) SkpB (D. melanogaster) SkpF (D. melanogaster) SkpC (D. melanogaster) SkpD (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)