ARAF - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARAF	ENSG00000078061	cholangiocarcinoma lung adenocarcinoma Langerhans cell histiocytosis	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer activity, downstream of receptor protein binding ATP binding metal ion binding	lin-45 (C. elegans)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)