NOTCH1 - NCK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
NCK1	ENSG00000158092	No diseases in record	No drugs in record	protein kinase inhibitor activity SH3/SH2 adaptor activity ARF guanyl-nucleotide exchange factor activity receptor binding protein binding cytoskeletal adaptor activity protein domain specific binding receptor signaling complex scaffold activity protein binding, bridging receptor tyrosine kinase binding ephrin receptor binding eukaryotic initiation factor eIF2 binding cadherin binding involved in cell-cell adhesion	nck-1 (C. elegans) dock (D. melanogaster)