NOTCH1 - CYP3A4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
CYP3A4	ENSG00000160868	No diseases in record	COBICISTAT	monooxygenase activity steroid binding iron ion binding steroid hydroxylase activity oxidoreductase activity oxygen binding enzyme binding heme binding vitamin D3 25-hydroxylase activity taurochenodeoxycholate 6alpha-hydroxylase activity caffeine oxidase activity albendazole monooxygenase activity quinine 3-monooxygenase activity testosterone 6-beta-hydroxylase activity aromatase activity vitamin D 24-hydroxylase activity estrogen 16-alpha-hydroxylase activity 1,8-cineole 2-exo-monooxygenase activity	Cyp6a9 (D. melanogaster) Cyp6a22 (D. melanogaster) Cyp6a21 (D. melanogaster) Cyp28d1 (D. melanogaster) Cyp28d2 (D. melanogaster)