NOTCH1 - DDX3X

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
DDX3X	ENSG00000215301	CLL medulloblastoma	No drugs in record	DNA binding RNA binding GTPase activity ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity protein binding ATP binding transcription factor binding poly(A) binding eukaryotic initiation factor 4E binding ATPase activity nucleoside-triphosphatase activity translation initiation factor binding RNA stem-loop binding ribosomal small subunit binding CTPase activity mRNA 5'-UTR binding cadherin binding involved in cell-cell adhesion	DBP1 (S. cerevisiae) DED1 (S. cerevisiae) bel (D. melanogaster)