Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
TOP2B
|
ENSG00000077097
|
No diseases in record
|
ETOPOSIDE
TENIPOSIDE
|
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
|
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
|
NOTCH1
|
ENSG00000148400
|
T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC
|
No drugs in record
|
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
enzyme inhibitor activity
receptor activity
Notch binding
calcium ion binding
protein binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
protein heterodimerization activity
|
N (D. melanogaster)
|