NOTCH1 - MCM7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
MCM7	ENSG00000166508	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding DNA binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity chromatin binding DNA replication origin binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity single-stranded DNA-dependent ATPase activity hydrolase activity nucleotide binding ATP-dependent four-way junction helicase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM7 (S. cerevisiae) Mcm7 (D. melanogaster)