NOTCH1 - PCSK9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
PCSK9	ENSG00000169174	No diseases in record	No drugs in record	serine-type endopeptidase activity protein binding sodium channel inhibitor activity low-density lipoprotein particle binding receptor inhibitor activity apolipoprotein binding very-low-density lipoprotein particle binding apolipoprotein receptor binding protein self-association low-density lipoprotein particle receptor binding very-low-density lipoprotein particle receptor binding	PRB1 (S. cerevisiae) RRT12 (S. cerevisiae) YSP3 (S. cerevisiae)