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NOTCH1 - FOXO1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
NOTCH1
ENSG00000148400
T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC
No drugs in record
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
enzyme inhibitor activity
receptor activity
Notch binding
calcium ion binding
protein binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
protein heterodimerization activity
N (D. melanogaster)
FOXO1
ENSG00000150907
alveolar rhabdomyosarcoma
No drugs in record
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator binding
chromatin binding
protein binding
beta-catenin binding
ubiquitin protein ligase binding
sequence-specific DNA binding
protein phosphatase 2A binding
HCM1 (S. cerevisiae)
daf-16 (C. elegans)
foxo (D. melanogaster)