EGFR - PTCH1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EGFR ENSG00000146648 glioma
NSCLC
AFATINIB
CETUXIMAB
ERLOTINIB
GEFITINIB
LAPATINIB
PANITUMUMAB
VANDETANIB
glycoprotein binding
chromatin binding
double-stranded DNA binding
MAP kinase kinase kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
integrin binding
protein binding
calmodulin binding
ATP binding
enzyme binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
epidermal growth factor binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nitric-oxide synthase regulator activity
protein domain specific binding
let-23 (C. elegans)
Egfr (D. melanogaster)
PTCH1 ENSG00000185920 skin basal cell
medulloblastoma

No drugs in record

patched binding
smoothened binding
protein binding
hedgehog receptor activity
heparin binding
cholesterol binding
cyclin binding
protein complex binding
hedgehog family protein binding
NCR1 (S. cerevisiae)
ptc-1 (C. elegans)
ptc-3 (C. elegans)
ptc-2 (C. elegans)
ptc (D. melanogaster)