CDC73 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDC73	ENSG00000134371	parathyroid adenoma multiple ossifying jaw fibroma	No drugs in record	RNA polymerase II core binding protein binding chromatin binding transcription factor activity, TFIIF-class transcription factor binding RNA polymerase II C-terminal domain phosphoserine binding transcription factor activity, RNA polymerase II transcription factor binding molecular_function	CDC73 (S. cerevisiae) hyx (D. melanogaster) CG6220 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)