SIRT1 - MARCH6

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
MARCH6	ENSG00000145495	No diseases in record	No drugs in record	ubiquitin-protein transferase activity zinc ion binding ligase activity enzyme binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding	SSM4 (S. cerevisiae) marc-6 (C. elegans) CG1317 (D. melanogaster)