MARCH6 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MARCH6	ENSG00000145495	No diseases in record	No drugs in record	ubiquitin-protein transferase activity zinc ion binding ligase activity enzyme binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding	SSM4 (S. cerevisiae) marc-6 (C. elegans) CG1317 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)