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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
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Experimentally Validated
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Cancer gene:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
CBLC
ENSG00000142273
H. sapiens
AML
phosphotyrosine residue binding
signal transducer activity
epidermal growth factor receptor binding
...
219
UTP11
ENSG00000183520
H. sapiens
protein binding
molecular_function
snoRNA binding
...
132
MT-CO1
ENSG00000198804
H. sapiens
iron ion binding
protein binding
heme binding
...
54
RBM4
ENSG00000173933
H. sapiens
nucleotide binding
RNA binding
mRNA binding
...
249
LIN9
ENSG00000183814
H. sapiens
protein binding
...
206
NR2F1
ENSG00000175745
H. sapiens
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription coactivator activity
...
269
MRPL55
ENSG00000162910
H. sapiens
structural constituent of ribosome
structural constituent of ribosome
...
42
GRIN1
ENSG00000176884
H. sapiens
ACAMPROSATE
AMANTADINE
FELBAMATE
KETAMINE
MEMANTINE
ORPHENADRINE
Ras guanyl-nucleotide exchange factor activity
receptor binding
extracellular-glutamate-gated ion channel activity
...
49
CSF1R
ENSG00000182578
H. sapiens
MDS
CML
AML
hemangioblastoma
CCRCC
PAZOPANIB
SUNITINIB
macrophage colony-stimulating factor receptor activity
ATP binding
protein phosphatase binding
...
130
CLK3
ENSG00000179335
H. sapiens
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
...
63
KCNA2
ENSG00000177301
H. sapiens
DALFAMPRIDINE
GUANIDINE
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
...
55
RIN1
ENSG00000174791
H. sapiens
GTPase activator activity
protein binding
Ras GTPase binding
...
283
LDB1
ENSG00000198728
H. sapiens
RNA polymerase II activating transcription factor binding
enhancer sequence-specific DNA binding
chromatin binding
...
60
SPRY2
ENSG00000136158
H. sapiens
protein binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
...
173
HNRNPA0
ENSG00000177733
H. sapiens
nucleotide binding
RNA binding
AU-rich element binding
...
338
ATG13
ENSG00000175224
H. sapiens
protein binding
protein kinase binding
protein kinase regulator activity
...
118
MAP3K11
ENSG00000173327
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
...
300
TLE1
ENSG00000196781
H. sapiens
RNA polymerase II transcription corepressor activity
protein binding
transcription factor binding
...
216
KMT5A
ENSG00000183955
H. sapiens
p53 binding
transcription corepressor activity
protein binding
...
266
SH2B1
ENSG00000178188
H. sapiens
signal transducer activity
protein binding
signaling adaptor activity
...
274
EXOC3
ENSG00000180104
H. sapiens
SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion
...
130
TRAIP
ENSG00000183763
H. sapiens
signal transducer activity, downstream of receptor
protein binding
zinc ion binding
...
208
SLC25A4
ENSG00000151729
H. sapiens
protein binding
adenine transmembrane transporter activity
...
170
HNRNPAB
ENSG00000197451
H. sapiens
nucleotide binding
RNA binding
mRNA binding
...
344
BANF1
ENSG00000175334
H. sapiens
DNA binding
protein binding
protein C-terminus binding
...
318
CASP7
ENSG00000165806
H. sapiens
cysteine-type endopeptidase activity
protein binding
cysteine-type peptidase activity
...
483
MRPL14
ENSG00000180992
H. sapiens
structural constituent of ribosome
structural constituent of ribosome
...
63
DTX3L
ENSG00000163840
H. sapiens
ubiquitin-protein transferase activity
protein binding
zinc ion binding
...
279
MYO6
ENSG00000196586
H. sapiens
motor activity
actin binding
protein binding
...
357
CLN3
ENSG00000188603
H. sapiens
protein binding
protein binding
unfolded protein binding
...
277
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