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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
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Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
PPID
ENSG00000171497
H. sapiens
peptidyl-prolyl cis-trans isomerase activity
protein binding
transcription factor binding
...
170
DRAP1
ENSG00000175550
H. sapiens
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
...
89
SHMT2
ENSG00000182199
H. sapiens
chromatin binding
glycine hydroxymethyltransferase activity
protein binding
...
167
TTC37
ENSG00000198677
H. sapiens
protein binding
...
392
WWOX
ENSG00000186153
H. sapiens
protein binding
oxidoreductase activity
enzyme binding
...
351
STT3B
ENSG00000163527
H. sapiens
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
...
74
RAD51B
ENSG00000182185
H. sapiens
lipoma
uterine leiomyoma
recombinase activity
DNA binding
double-stranded DNA binding
...
139
MYO1C
ENSG00000197879
H. sapiens
microfilament motor activity
actin binding
receptor binding
...
297
PAK2
ENSG00000180370
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
...
523
TXNRD1
ENSG00000198431
H. sapiens
ARSENIC TRIOXIDE
thioredoxin-disulfide reductase activity
protein binding
electron carrier activity
...
187
TUBB6
ENSG00000176014
H. sapiens
BRENTUXIMAB VEDOTIN
CABAZITAXEL
COLCHICINE
DOCETAXEL
ERIBULIN
IXABEPILONE
PACLITAXEL
TRASTUZUMAB EMTANSINE
VINBLASTINE
VINCRISTINE
VINORELBINE BASE
molecular_function
GTPase activity
structural constituent of cytoskeleton
...
253
UBE2E1
ENSG00000170142
H. sapiens
ubiquitin-protein transferase activity
protein binding
ATP binding
...
319
PRKD1
ENSG00000184304
H. sapiens
protein serine/threonine kinase activity
protein kinase C activity
protein binding
...
305
USP18
ENSG00000184979
H. sapiens
thiol-dependent ubiquitin-specific protease activity
protein binding
ISG15-specific protease activity
...
157
GATA2
ENSG00000179348
H. sapiens
AML
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
...
92
ZFAND4
ENSG00000172671
H. sapiens
zinc ion binding
...
102
CSTF2T
ENSG00000177613
H. sapiens
nucleotide binding
mRNA binding
protein binding
...
211
HIST4H4
ENSG00000197837
H. sapiens
...
254
HIST1H3J
ENSG00000197153
H. sapiens
...
100
TOM1L2
ENSG00000175662
H. sapiens
protein binding
protein kinase binding
clathrin binding
...
186
TADA2B
ENSG00000173011
H. sapiens
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
...
44
CCNE2
ENSG00000175305
H. sapiens
protein binding
cyclin-dependent protein serine/threonine kinase regulator activity
protein kinase binding
...
265
UBQLN2
ENSG00000188021
H. sapiens
protein binding
...
501
FOXO4
ENSG00000184481
H. sapiens
AL
soft tissue sarcoma
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
...
375
BCOR
ENSG00000183337
H. sapiens
retinoblastoma
AML
APL
transcription corepressor activity
protein binding
transcription factor binding
...
255
XPOT
ENSG00000184575
H. sapiens
tRNA binding
Ran GTPase binding
nucleobase-containing compound transmembrane transporter activity
...
167
DLL1
ENSG00000198719
H. sapiens
Notch binding
Notch binding
calcium ion binding
...
240
MRPL21
ENSG00000197345
H. sapiens
structural constituent of ribosome
structural constituent of ribosome
RNA binding
...
51
HIBCH
ENSG00000198130
H. sapiens
3-hydroxyisobutyryl-CoA hydrolase activity
...
83
DDX42
ENSG00000198231
H. sapiens
ATP-dependent RNA helicase activity
protein binding
ATP binding
...
170
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