Genes

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Gene Ensembl ID Organism Diseases Drugs Ontology Interactions
TRAF6 ENSG00000175104 H. sapiens ubiquitin-protein transferase activity tumor necrosis factor receptor binding protein binding ... 2498
UBE2O ENSG00000175931 H. sapiens ubiquitin-protein transferase activity protein binding ATP binding ... 186
SMAD2 ENSG00000175387 H. sapiens colorectal carcinoma hepatocellular carcinoma RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding ... 2075
TYMS ENSG00000176890 H. sapiens CAPECITABINE FLOXURIDINE FLUOROURACIL GEMCITABINE PEMETREXED nucleotide binding mRNA binding thymidylate synthase activity ... 273
PPP1CA ENSG00000172531 H. sapiens phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein binding ... 1797
UBE2N ENSG00000177889 H. sapiens ubiquitin-protein transferase activity protein binding ATP binding ... 1611
SMARCC1 ENSG00000173473 H. sapiens transcription coactivator activity protein binding protein N-terminus binding ... 885
EIF3F ENSG00000175390 H. sapiens translation initiation factor activity translation initiation factor activity thiol-dependent ubiquitin-specific protease activity ... 763
ERBB4 ENSG00000178568 H. sapiens melanoma gastric NSCLC AFATINIB VANDETANIB protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity ... 1451
JUN ENSG00000177606 H. sapiens sarcoma RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding ... 2847
GAK ENSG00000178950 H. sapiens protein serine/threonine kinase activity protein binding ATP binding ... 543
DMAP1 ENSG00000178028 H. sapiens RNA polymerase II repressing transcription factor binding transcription corepressor activity protein binding ... 241
ERCC4 ENSG00000175595 H. sapiens skin basal cell skin squamous cell melanoma single-stranded DNA endodeoxyribonuclease activity TFIID-class transcription factor binding damaged DNA binding ... 248
HRAS ENSG00000174775 H. sapiens infrequent sarcomas rare other tumour types rhabdomyosarcoma ganglioneuroblastoma bladder GTPase activity GTPase activity protein binding ... 1007
ANAPC2 ENSG00000176248 H. sapiens ubiquitin protein ligase binding ubiquitin protein ligase activity ... 462
RRS1 ENSG00000179041 H. sapiens protein binding molecular_function protein binding ... 149
SETD2 ENSG00000181555 H. sapiens clear cell renal carcinoma protein binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K36 specific) ... 123
NOP10 ENSG00000182117 H. sapiens protein binding box H/ACA snoRNA binding telomerase RNA binding ... 147
NPM1 ENSG00000181163 H. sapiens NHL APL AML transcription coactivator activity RNA binding protein kinase inhibitor activity ... 1396
RAD23A ENSG00000179262 H. sapiens damaged DNA binding single-stranded DNA binding protein binding ... 755
TBK1 ENSG00000183735 H. sapiens nucleic acid binding protein kinase activity protein serine/threonine kinase activity ... 1162
AURKB ENSG00000178999 H. sapiens protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein binding ... 785
ALYREF ENSG00000183684 H. sapiens nucleotide binding protein binding ... 1503
RUVBL2 ENSG00000183207 H. sapiens RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding DNA helicase activity ... 1890
YES1 ENSG00000176105 H. sapiens DASATINIB protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity receptor binding ... 2071
SF3A3 ENSG00000183431 H. sapiens RNA binding protein binding zinc ion binding ... 931
UQCR10 ENSG00000184076 H. sapiens ubiquinol-cytochrome-c reductase activity ... 70
UBE2G2 ENSG00000184787 H. sapiens ubiquitin-protein transferase activity protein binding ATP binding ... 407
SOCS3 ENSG00000184557 H. sapiens protein kinase inhibitor activity protein binding ... 243
SP1 ENSG00000185591 H. sapiens RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding ... 2646