TOP2

YNL088W - S. cerevisiae

Pathways

Go term Description
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005524 ATP binding
GO:0003677 DNA binding
GO:0000166 nucleotide binding
GO:0003916 DNA topoisomerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0000400 four-way junction DNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0003682 chromatin binding
GO:0000182 rDNA binding
GO:0003696 satellite DNA binding
GO:0061505 DNA topoisomerase II activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2A H. sapiens
TOP2B H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDR502C SAM2 YNL088W TOP2 S. cerevisiae SDL Slorth 0.942417 View
YDL042C SIR2 YNL088W TOP2 S. cerevisiae SDL Slorth 0.942239 View
YNL088W TOP2 YPR023C EAF3 S. cerevisiae SSL Slorth 0.94196 View
YNL088W TOP2 YOL034W SMC5 S. cerevisiae SDL Slorth 0.940731 View
YNL088W TOP2 YOR123C LEO1 S. cerevisiae SSL Slorth 0.940459 View
YNL088W TOP2 YOR141C ARP8 S. cerevisiae SSL Slorth 0.939422 View
YMR224C MRE11 YNL088W TOP2 S. cerevisiae SDL Slorth 0.938579 View
YNL088W TOP2 YOR061W CKA2 S. cerevisiae SSL Slorth 0.938324 View
YNL088W TOP2 YOL012C HTZ1 S. cerevisiae SSL Slorth 0.937717 View
YMR224C MRE11 YNL088W TOP2 S. cerevisiae SSL Slorth 0.93744 View
YNL088W TOP2 YNL097C PHO23 S. cerevisiae SSL Slorth 0.937084 View
YMR001C CDC5 YNL088W TOP2 S. cerevisiae SDL Slorth 0.937033 View
YGL190C CDC55 YNL088W TOP2 S. cerevisiae SSL Slorth 0.93665 View
YIR004W DJP1 YNL088W TOP2 S. cerevisiae SDL Slorth 0.936407 View
YDR510W SMT3 YNL088W TOP2 S. cerevisiae SSL Slorth 0.936294 View
YNL021W HDA1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.936256 View
YLR085C ARP6 YNL088W TOP2 S. cerevisiae SSL Slorth 0.936029 View
YDR180W SCC2 YNL088W TOP2 S. cerevisiae SSL Slorth 0.935718 View
YLR234W TOP3 YNL088W TOP2 S. cerevisiae SDL Slorth 0.935697 View
YGL244W RTF1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.934009 View
YBR231C SWC5 YNL088W TOP2 S. cerevisiae SSL Slorth 0.933752 View
YLR383W SMC6 YNL088W TOP2 S. cerevisiae SSL Slorth 0.932971 View
YLR045C STU2 YNL088W TOP2 S. cerevisiae SSL Slorth 0.931536 View
YNL088W TOP2 YOR191W ULS1 S. cerevisiae SSL Slorth 0.931284 View
YHR166C CDC23 YNL088W TOP2 S. cerevisiae SSL Slorth 0.931016 View
YBL008W HIR1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.930659 View
YNL088W TOP2 YNL107W YAF9 S. cerevisiae SSL Slorth 0.930347 View
YDL070W BDF2 YNL088W TOP2 S. cerevisiae SDL Slorth 0.930305 View
YBR089C-A NHP6B YNL088W TOP2 S. cerevisiae SDL Slorth 0.930199 View
YDR392W SPT3 YNL088W TOP2 S. cerevisiae SSL Slorth 0.930175 View
YKL022C CDC16 YNL088W TOP2 S. cerevisiae SSL Slorth 0.927809 View
YLR399C BDF1 YNL088W TOP2 S. cerevisiae SDL Slorth 0.927769 View
YNL088W TOP2 YNL250W RAD50 S. cerevisiae SSL Slorth 0.927754 View
YBL105C PKC1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.927311 View
YNL088W TOP2 YNL153C GIM3 S. cerevisiae SSL Slorth 0.927 View
YLR399C BDF1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.926992 View
YIL126W STH1 YNL088W TOP2 S. cerevisiae SDL Slorth 0.926901 View
YDL101C DUN1 YNL088W TOP2 S. cerevisiae SSL Slorth 0.926667 View
YDR145W TAF12 YNL088W TOP2 S. cerevisiae SSL Slorth 0.926292 View
YNL088W TOP2 YNL261W ORC5 S. cerevisiae SSL Slorth 0.925846 View