POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000007168 PAFAH1B1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.84611 View
ENSG00000101868 POLA1 ENSG00000135312 HTR1B H. sapiens SSL Slorth 0.846025 View
ENSG00000101868 POLA1 ENSG00000127337 YEATS4 H. sapiens SSL Slorth 0.84602 View
ENSG00000072803 FBXW11 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.845792 View
ENSG00000101161 PRPF6 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.845739 View
ENSG00000101868 POLA1 ENSG00000136014 USP44 H. sapiens SSL Slorth 0.845691 View
ENSG00000101868 POLA1 ENSG00000185896 LAMP1 H. sapiens SSL Slorth 0.845665 View
ENSG00000101868 POLA1 ENSG00000171150 SOCS5 H. sapiens SSL Slorth 0.845665 View
ENSG00000101868 POLA1 ENSG00000183665 TRMT12 H. sapiens SSL Slorth 0.845589 View
ENSG00000101868 POLA1 ENSG00000171634 BPTF H. sapiens SSL Slorth 0.845497 View
ENSG00000101868 POLA1 ENSG00000154059 IMPACT H. sapiens SSL Slorth 0.845291 View
ENSG00000101868 POLA1 ENSG00000176095 IP6K1 H. sapiens SSL Slorth 0.845286 View
ENSG00000101868 POLA1 ENSG00000197548 ATG7 H. sapiens SSL Slorth 0.845207 View
ENSG00000101868 POLA1 ENSG00000155760 FZD7 H. sapiens SSL Slorth 0.845184 View
ENSG00000101868 POLA1 ENSG00000164654 MIOS H. sapiens SSL Slorth 0.845079 View
ENSG00000101868 POLA1 ENSG00000196792 STRN3 H. sapiens SSL Slorth 0.844599 View
ENSG00000101868 POLA1 ENSG00000126215 XRCC3 H. sapiens SSL Slorth 0.844141 View
ENSG00000101868 POLA1 ENSG00000143437 ARNT H. sapiens SSL Slorth 0.84408 View
ENSG00000101868 POLA1 ENSG00000108590 MED31 H. sapiens SSL Slorth 0.84373 View
ENSG00000101868 POLA1 ENSG00000135503 ACVR1B H. sapiens SSL Slorth 0.843686 View
ENSG00000101868 POLA1 ENSG00000112039 FANCE H. sapiens SSL Slorth 0.843591 View
ENSG00000101868 POLA1 ENSG00000143507 DUSP10 H. sapiens SSL Slorth 0.843429 View
ENSG00000101336 HCK ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.84341 View
ENSG00000101868 POLA1 ENSG00000156345 CDK20 H. sapiens SSL Slorth 0.843353 View
ENSG00000101868 POLA1 ENSG00000102996 MMP15 H. sapiens SSL Slorth 0.843129 View
ENSG00000101868 POLA1 ENSG00000149968 MMP3 H. sapiens SSL Slorth 0.843129 View
ENSG00000101868 POLA1 ENSG00000160075 SSU72 H. sapiens SSL Slorth 0.843129 View
ENSG00000101868 POLA1 ENSG00000120693 SMAD9 H. sapiens SSL Slorth 0.843005 View
ENSG00000101868 POLA1 ENSG00000160255 ITGB2 H. sapiens SSL Slorth 0.842725 View
ENSG00000101868 POLA1 ENSG00000247746 USP51 H. sapiens SSL Slorth 0.842533 View
ENSG00000101868 POLA1 ENSG00000135837 CEP350 H. sapiens SSL Slorth 0.842518 View
ENSG00000101868 POLA1 ENSG00000110048 OSBP H. sapiens SSL Slorth 0.842453 View
ENSG00000101868 POLA1 ENSG00000256206 RP11-140L24.4 H. sapiens SSL Slorth 0.842371 View
ENSG00000101868 POLA1 ENSG00000115694 STK25 H. sapiens SSL Slorth 0.842329 View
ENSG00000101868 POLA1 ENSG00000154719 MRPL39 H. sapiens SSL Slorth 0.842269 View
ENSG00000101868 POLA1 ENSG00000169220 RGS14 H. sapiens SSL Slorth 0.842119 View
ENSG00000101868 POLA1 ENSG00000197635 DPP4 H. sapiens SSL Slorth 0.841882 View
ENSG00000101868 POLA1 ENSG00000130299 GTPBP3 H. sapiens SSL Slorth 0.841882 View
ENSG00000101868 POLA1 ENSG00000169016 E2F6 H. sapiens SSL Slorth 0.841803 View
ENSG00000101868 POLA1 ENSG00000152601 MBNL1 H. sapiens SSL Slorth 0.84178 View