POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000135966 TGFBRAP1 H. sapiens SSL Slorth 0.883453 View
ENSG00000101868 POLA1 ENSG00000164597 COG5 H. sapiens SSL Slorth 0.88342 View
ENSG00000101868 POLA1 ENSG00000168434 COG7 H. sapiens SSL Slorth 0.88342 View
ENSG00000101868 POLA1 ENSG00000124222 STX16 H. sapiens SSL Slorth 0.883407 View
ENSG00000101868 POLA1 ENSG00000115806 GORASP2 H. sapiens SSL Slorth 0.883395 View
ENSG00000101868 POLA1 ENSG00000185513 L3MBTL1 H. sapiens SSL Slorth 0.883361 View
ENSG00000101868 POLA1 ENSG00000147050 KDM6A H. sapiens SSL Slorth 0.883349 View
ENSG00000101868 POLA1 ENSG00000143473 KCNH1 H. sapiens SSL Slorth 0.883285 View
ENSG00000101868 POLA1 ENSG00000174579 MSL2 H. sapiens SSL Slorth 0.883244 View
ENSG00000101868 POLA1 ENSG00000140396 NCOA2 H. sapiens SSL Slorth 0.883228 View
ENSG00000101868 POLA1 ENSG00000185950 IRS2 H. sapiens SSL Slorth 0.88321 View
ENSG00000101868 POLA1 ENSG00000266173 STRADA H. sapiens SSL Slorth 0.883152 View
ENSG00000101868 POLA1 ENSG00000135144 DTX1 H. sapiens SSL Slorth 0.883138 View
ENSG00000101868 POLA1 ENSG00000106384 MOGAT3 H. sapiens SSL Slorth 0.883053 View
ENSG00000101868 POLA1 ENSG00000128731 HERC2 H. sapiens SSL Slorth 0.883002 View
ENSG00000101868 POLA1 ENSG00000119541 VPS4B H. sapiens SSL Slorth 0.882861 View
ENSG00000101868 POLA1 ENSG00000140678 ITGAX H. sapiens SSL Slorth 0.882836 View
ENSG00000101868 POLA1 ENSG00000151748 SAV1 H. sapiens SSL Slorth 0.882779 View
ENSG00000101868 POLA1 ENSG00000166562 SEC11C H. sapiens SSL Slorth 0.88275 View
ENSG00000101868 POLA1 ENSG00000112715 VEGFA H. sapiens SSL Slorth 0.882654 View
ENSG00000101868 POLA1 ENSG00000168646 AXIN2 H. sapiens SSL Slorth 0.882615 View
ENSG00000101868 POLA1 ENSG00000103051 COG4 H. sapiens SSL Slorth 0.882575 View
ENSG00000101868 POLA1 ENSG00000182979 MTA1 H. sapiens SSL Slorth 0.882575 View
ENSG00000101868 POLA1 ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.882538 View
ENSG00000101868 POLA1 ENSG00000163625 WDFY3 H. sapiens SSL Slorth 0.882505 View
ENSG00000101868 POLA1 ENSG00000136715 SAP130 H. sapiens SSL Slorth 0.882451 View
ENSG00000101868 POLA1 ENSG00000204390 HSPA1L H. sapiens SSL Slorth 0.882401 View
ENSG00000101868 POLA1 ENSG00000165506 DNAAF2 H. sapiens SSL Slorth 0.882401 View
ENSG00000101868 POLA1 ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.882387 View
ENSG00000101868 POLA1 ENSG00000102225 CDK16 H. sapiens SSL Slorth 0.882273 View
ENSG00000101868 POLA1 ENSG00000178741 COX5A H. sapiens SSL Slorth 0.882245 View
ENSG00000101868 POLA1 ENSG00000117425 PTCH2 H. sapiens SSL Slorth 0.882131 View
ENSG00000101868 POLA1 ENSG00000164190 NIPBL H. sapiens SSL Slorth 0.882116 View
ENSG00000101868 POLA1 ENSG00000123080 CDKN2C H. sapiens SSL Slorth 0.882108 View
ENSG00000101868 POLA1 ENSG00000184182 UBE2F H. sapiens SSL Slorth 0.882094 View
ENSG00000101868 POLA1 ENSG00000130589 HELZ2 H. sapiens SSL Slorth 0.881986 View
ENSG00000101868 POLA1 ENSG00000109103 UNC119 H. sapiens SSL Slorth 0.88195 View
ENSG00000101868 POLA1 ENSG00000183474 GTF2H2C H. sapiens SSL Slorth 0.881899 View
ENSG00000101868 POLA1 ENSG00000170043 TRAPPC1 H. sapiens SSL Slorth 0.881879 View
ENSG00000101868 POLA1 ENSG00000125503 PPP1R12C H. sapiens SSL Slorth 0.881837 View