ERBB3

ENSG00000065361 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004888 transmembrane signaling receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0030296 protein tyrosine kinase activator activity
GO:0038132 neuregulin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
colon
gastric
head and neck
bladder
skin

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000055130 CUL1 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.898533 View
ENSG00000058729 RIOK2 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.892103 View
ENSG00000004897 CDC27 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.887738 View
ENSG00000049759 NEDD4L ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.878212 View
ENSG00000036257 CUL3 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.876499 View
ENSG00000061938 TNK2 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.866251 View
ENSG00000065361 ERBB3 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.857421 View
ENSG00000039068 CDH1 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.851448 View
ENSG00000006451 RALA ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.846041 View
ENSG00000044574 HSPA5 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.824138 View
ENSG00000005007 UPF1 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.783153 View
ENSG00000065361 ERBB3 ENSG00000101665 SMAD7 H. sapiens SSL Slorth 0.781612 View
ENSG00000023445 BIRC3 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.779904 View
ENSG00000065361 ERBB3 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.77695 View
ENSG00000064012 CASP8 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.776202 View
ENSG00000065361 ERBB3 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.771403 View
ENSG00000065361 ERBB3 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.761538 View
ENSG00000047315 POLR2B ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.753858 View