CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000177733 HNRNPA0 H. sapiens SSL Slorth 0.852256 View
ENSG00000106799 TGFBR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.852234 View
ENSG00000090372 STRN4 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.851866 View
ENSG00000135446 CDK4 ENSG00000184260 HIST2H2AC H. sapiens SSL Slorth 0.851787 View
ENSG00000013503 POLR3B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.851452 View
ENSG00000135446 CDK4 ENSG00000177565 TBL1XR1 H. sapiens SSL Slorth 0.851329 View
ENSG00000101367 MAPRE1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.851311 View
ENSG00000135446 CDK4 ENSG00000179218 CALR H. sapiens SSL Slorth 0.851146 View
ENSG00000010292 NCAPD2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.850654 View
ENSG00000135446 CDK4 ENSG00000149269 PAK1 H. sapiens SSL Slorth 0.85054 View
ENSG00000104969 SGTA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.850456 View
ENSG00000135446 CDK4 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.850346 View
ENSG00000112576 CCND3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.850297 View
ENSG00000112237 CCNC ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.849577 View
ENSG00000131876 SNRPA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.849389 View
ENSG00000135446 CDK4 ENSG00000143256 PFDN2 H. sapiens SSL Slorth 0.849007 View
ENSG00000135446 CDK4 ENSG00000171132 PRKCE H. sapiens SSL Slorth 0.84862 View
ENSG00000135446 CDK4 ENSG00000138814 PPP3CA H. sapiens SSL Slorth 0.848518 View
ENSG00000126351 THRA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.848292 View
ENSG00000135446 CDK4 ENSG00000174738 NR1D2 H. sapiens SSL Slorth 0.848251 View
ENSG00000135446 CDK4 ENSG00000160294 MCM3AP H. sapiens SSL Slorth 0.848213 View
ENSG00000135446 CDK4 ENSG00000148484 RSU1 H. sapiens SSL Slorth 0.848028 View
ENSG00000115129 TP53I3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.847827 View
ENSG00000135446 CDK4 ENSG00000183072 NKX2-5 H. sapiens SSL Slorth 0.847789 View
ENSG00000122728 TAF1L ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.847416 View
ENSG00000134987 WDR36 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.847307 View
ENSG00000135446 CDK4 ENSG00000138778 CENPE H. sapiens SSL Slorth 0.847148 View
ENSG00000135446 CDK4 ENSG00000168118 RAB4A H. sapiens SSL Slorth 0.847026 View
ENSG00000124422 USP22 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.846814 View
ENSG00000135446 CDK4 ENSG00000148737 TCF7L2 H. sapiens SSL Slorth 0.846771 View
ENSG00000135446 CDK4 ENSG00000163931 TKT H. sapiens SSL Slorth 0.846669 View
ENSG00000135446 CDK4 ENSG00000228425 VPS52 H. sapiens SSL Slorth 0.846111 View
ENSG00000077150 NFKB2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.845475 View
ENSG00000135446 CDK4 ENSG00000198176 TFDP1 H. sapiens SSL Slorth 0.845193 View
ENSG00000135446 CDK4 ENSG00000148660 CAMK2G H. sapiens SSL Slorth 0.84517 View
ENSG00000108510 MED13 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.845091 View
ENSG00000135446 CDK4 ENSG00000179041 RRS1 H. sapiens SSL Slorth 0.844959 View
ENSG00000135446 CDK4 ENSG00000220205 VAMP2 H. sapiens SSL Slorth 0.844957 View
ENSG00000125630 POLR1B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.844586 View
ENSG00000135446 CDK4 ENSG00000173933 RBM4 H. sapiens SSL Slorth 0.844566 View