SAE1 - SMAD1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SAE1	ENSG00000142230	No diseases in record	No drugs in record	ubiquitin activating enzyme activity protein binding protein C-terminus binding enzyme activator activity ATP-dependent protein binding protein heterodimerization activity SUMO activating enzyme activity	AOS1 (S. cerevisiae) Aos1 (D. melanogaster)
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)