SAE1 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SAE1	ENSG00000142230	No diseases in record	No drugs in record	ubiquitin activating enzyme activity protein binding protein C-terminus binding enzyme activator activity ATP-dependent protein binding protein heterodimerization activity SUMO activating enzyme activity	AOS1 (S. cerevisiae) Aos1 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)