TPR - ERBB2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TPR	ENSG00000047410	papillary thyroid NSCLC	No drugs in record	molecular_function chromatin binding mRNA binding nucleocytoplasmic transporter activity protein binding tubulin binding heat shock protein binding protein homodimerization activity mitogen-activated protein kinase binding dynein complex binding transporter activity protein anchor	Mtor (D. melanogaster)
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)