IL6ST - ERBB2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IL6ST	ENSG00000134352	hepatocellular carcinoma	TOCILIZUMAB	ciliary neurotrophic factor receptor activity interleukin-11 receptor activity ciliary neurotrophic factor receptor binding protein binding growth factor binding interleukin-11 binding protein homodimerization activity interleukin-27 receptor activity interleukin-6 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity interleukin-6 receptor binding interleukin-6 binding	No GO terms in record
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)