HMGA1 - ERBB2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGA1	ENSG00000137309	microfollicular thyroid adenoma various benign mesenchymal tumours	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding enzyme binding ligand-dependent nuclear receptor transcription coactivator activity retinoic acid receptor binding peroxisome proliferator activated receptor binding retinoid X receptor binding	No GO terms in record
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)