CREB1 - ERBB2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
CREB1 ENSG00000118260 clear cell sarcoma
angiomatoid fibrous histiocytoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription cofactor activity
protein binding
enzyme binding
Hsp70 protein binding
histone acetyltransferase binding
cAMP response element binding
identical protein binding
arrestin family protein binding

No GO terms in record

ERBB2 ENSG00000141736 breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity
growth factor binding
let-23 (C. elegans)
Egfr (D. melanogaster)