ERBB2 - DAXX

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
DAXX	ENSG00000204209	pancreatic neuroendocrine tumour paediatric glioblastoma	No drugs in record	p53 binding transcription corepressor activity signal transducer activity, downstream of receptor protein binding enzyme binding protein kinase binding protein kinase activator activity heat shock protein binding ubiquitin protein ligase binding histone binding protein N-terminus binding androgen receptor binding	No GO terms in record