ERBB2 - FLNA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
FLNA	ENSG00000196924	phyllodes tumour of the breast	No drugs in record	G-protein coupled receptor binding glycoprotein binding signal transducer activity protein binding transcription factor binding potassium channel regulator activity Rho GTPase binding Ral GTPase binding kinase binding small GTPase binding mu-type opioid receptor binding Fc-gamma receptor I complex binding protein homodimerization activity ion channel binding SMAD binding Rac GTPase binding actin filament binding GTPase binding cadherin binding involved in cell-cell adhesion	No GO terms in record