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Slorth
TDP1 - ERBB2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TDP1
ENSG00000042088
No diseases in record
No drugs in record
double-stranded DNA binding
single-stranded DNA binding
exonuclease activity
protein binding
3'-tyrosyl-DNA phosphodiesterase activity
hydrolase activity
nuclease activity
5'-tyrosyl-DNA phosphodiesterase activity
phosphoric diester hydrolase activity
TDP1 (S. cerevisiae)
gkt (D. melanogaster)
ERBB2
ENSG00000141736
breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity
growth factor binding
let-23 (C. elegans)
Egfr (D. melanogaster)