ERBB2 - CLP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
CLP1	ENSG00000172409	AML	No drugs in record	ATP binding ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity polydeoxyribonucleotide kinase activity ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity RNA binding nucleotide binding polynucleotide 5'-hydroxyl-kinase activity protein serine/threonine phosphatase activity phosphoprotein phosphatase activity protein binding protein tyrosine phosphatase activity	CLP1 (S. cerevisiae) clpf-1 (C. elegans) cbc (D. melanogaster)