RB1 - EXO1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)
EXO1	ENSG00000174371	No diseases in record	No drugs in record	DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity 5'-flap endonuclease activity hydrolase activity catalytic activity nuclease activity hydrolase activity, acting on ester bonds double-stranded DNA binding	DIN7 (S. cerevisiae) EXO1 (S. cerevisiae) exo-1 (C. elegans) tos (D. melanogaster)