FOXO3 - USP8

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FOXO3	ENSG00000118689	AL	No drugs in record	core promoter binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding protein kinase binding chromatin DNA binding sequence-specific DNA binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)
USP8	ENSG00000138592	corticotroph adenoma	No drugs in record	cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding SH3 domain binding cadherin binding involved in cell-cell adhesion	DOA4 (S. cerevisiae) UBP5 (S. cerevisiae)