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USP8 - JAK1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
USP8
ENSG00000138592
corticotroph adenoma
No drugs in record
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
SH3 domain binding
cadherin binding involved in cell-cell adhesion
DOA4 (S. cerevisiae)
UBP5 (S. cerevisiae)
JAK1
ENSG00000162434
ALL
RUXOLITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding
hop (D. melanogaster)